The Project

The Brighton Marathon Research Group are conducting a research project at the 2017 Brighton Marathon. We are investigating changes in the levels of a protein called troponin during marathon running.

Troponin is a protein present in the cells of the heart that is released into the blood when the heart muscle is stressed or damaged. Previous studies have demonstrated that exercise can cause a rise in troponin levels. This study will increase our understanding of the significance of this rise.

Part of this project is to compare troponin levels between runners with or without heart disease (e.g. valvular heart disease, atrial fibrillation, ischaemic heart disease, cardiomyopathy or hypertension with left ventricular hypertrophy). We are therefore particularly keen to recruit runners with these conditions.

The project is split into 2 studies and you may participate in either study.

Study 1

Study 1 will involve you providing a blood sample (3 mls – a teaspoon) before the race at the time of the pre-race exhibition and also after the race. You can find more information about study 1 here.

Study 2

Study 2 will involve you participating in an exercise test (lasting 15 mins) 1-2 weeks before the marathon and wearing a heart rate monitor provided by us during the marathon. We will also ask for blood before and after the marathon similar to study 1. You can find more about study 2 here.

If you are interested in participating then please fill in this short form so we can send you the right information alternatively email bmheartstudy@gmail.com with any questions.

Study 1

This study involves you with providing a small sample of blood before (at the pre-race exhibition) and after the marathon.

The study is split into 2. You can participate in either study 1a or study 1a and 1b.

Study 1a – this will require 2 blood samples. The first sample will be taken at the pre-race exhibition and the second sample will be taken shortly after you finish the race in the finish line medical tent.

Study 1b – in addition to the above, blood samples will be taken 1, 3, 6 and 24 hours after you finish the marathon. These blood samples will be taken at the Brighton Hilton Hotel and you will be provided with a meal voucher to help you recover and refuel whilst you wait.

If you are interested in participating then please fill in this short form so we can send you the right information alternatively email bmheartstudy@gmail.com with any questions.

Study 2

This study involves you completing a short exercise test at the University of Brighton sport science laboratories in Eastbourne (20 miles east of Brighton). You will be able to complete the exercise test on the 18th March, 19th March, 25th March or 26th March. The whole process should take no longer than 1 hour, with the exercise test consisting of a maximum 20 minutes of running.

Location – Welkin Laboratories, University of Brighton, Carlisle Road, Eastbourne. BN20 7SP

What to bring – running attire, a drink and a towel and change of clothes if you wish to have a shower afterwards.

We would next see you at the pre-race exhibition where we would take a small sample of blood (3mls – a teaspoon) and provide you with a heart rate monitor to wear during the race.

At the finish line we would take another small sample of blood and collect the heart rate monitor.

If you are interested in participating then please fill in this short form so we can send you the right information alternatively email bmheartstudy@gmail.com with any questions.