The Brighton Marathon Research Group are conducting a research project at the 2017 Brighton Marathon. We are investigating changes in the levels of a protein called troponin during marathon running.
Troponin is a protein present in the cells of the heart that is released into the blood when the heart muscle is stressed or damaged. Previous studies have demonstrated that exercise can cause a rise in troponin levels. This study will increase our understanding of the significance of this rise.
Part of this project is to compare troponin levels between runners with or without heart disease (e.g. valvular heart disease, atrial fibrillation, ischaemic heart disease, cardiomyopathy or hypertension with left ventricular hypertrophy). We are therefore particularly keen to recruit runners with these conditions.
The project is split into 2 studies and you may participate in either study.
Study 1 will involve you providing a blood sample (3 mls – a teaspoon) before the race at the time of the pre-race exhibition and also after the race. You can find more information about study 1 here.
Study 2 will involve you participating in an exercise test (lasting 15 mins) 1-2 weeks before the marathon and wearing a heart rate monitor provided by us during the marathon. We will also ask for blood before and after the marathon similar to study 1. You can find more about study 2 here.